(1)The number one thing you absolutely need is a regular HB No.2 pencil so that you can rough out your ideas for your comic strip.
(2)The next thing that you'll need are some black ink pens. I mainly use Precise V5 pilot and Uni-ball pens. You use black ink pens to make your comics bolder and darker than pencil lines.(3)Any ol' eraser will work fine for erasing leftover pencil lines.
(4)&(5)A standard 1 foot ruler works fine for drawing cartoon panels. My panels are "3x3" but you can do them as big or as small as you like.
(6) Color is an option, but it makes your comics look much better than just black ink.
(7) Your imagination is one of the main things that you need to make your comic as crazy as you
want. Maybe a robot dog living in the NASA space shuttle... Whatever you want...
